The Functional Systems Manufacturing Branch (AFRL/RXME) plans and executes manufacturing technology and DPA Title III programs to establish and maintain the domestic industrial capability necessary for affordable manufacture of materials, devices, assemblies and subsystems for use in DAF and DoD weapon systems by advancing the state of the art in electronics manufacturing technologies. The branch is led by Alan Albert with John Cullum serving as Branch Technical Advisor.

The Digital Manufacturing and Supply Chain Branch (RXMD) focuses on advancing the state of the art in digital manufacturing technologies to include developing investment strategies in support of the same. This branch also executes the Industrial Base Assessment program that provides accurate and timely industrial base information to decision makers across the Department of the Air Force and helps manage the Defense Priorities and Allocation System for all Air Force weapon system programs. The Branch Chief is Rob Wittman with Dr. Bill Bernstein serving as the Branch Technical Advisor.

The Structural Systems Branch (RXMS) develops manufacturing technologies for structural and propulsion systems. Major initiatives include hypersonics structures and additive manufacturing.  Projects in these areas include materials processing, fabrication, assembly, integration, test, and quality improvement. Major Justin Carl serves as Branch Chief while Bryan Bojanowski is the Branch Technical Advisor.

The newest branch is the AFRL Energy Office (RXMZ).  RXMZ leads the discovery, development, and delivery of energy and climate science, technology, and innovation, and partners with DAF, DoD, DoE, and private sector innovation pipelines.  Its mission is to decouple mission effectiveness from energy, water, and other resource and supply chain vulnerabilities through the identification, development, and demonstration of critical technologies for the DAF.  The branch is led by Lt Col Charles Harding with Eric Griesenbrock as the Branch Technical Advisor.